Biochemical Aspects of Competence in the Bacillus subtilis Transformation System

نویسندگان

  • F. E. Young
  • J. Spizizen
چکیده

A lytic factor, associated with the cell wall, was fortuitously discovered during the course of the investigations described in the previous paper (1). In the pneumococcal transformation system (2-5) as well as in the Bacillus subtilis transformation system (6), the highly transformable strains possessed active autolytic enzymes. Consequently, studies were undertaken to investigate the relationship of this lytic factor to competence and to explore the mechanism of this reaction. The evidence presented below demonstrates that this lytic factor is an enzyme which cleaves the cell wall into heteropolymers. The activity of this enzyme is greater in the transformable strain.

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تاریخ انتشار 2003